What is Aceclofenac?
Aceclofenac is a commonly prescribed non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and swelling in various musculoskeletal and inflammatory conditions. It works by reducing the production of chemicals in the body that cause pain and inflammation.
Aceclofenac is widely used in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute pain conditions under medical supervision.
Drug Classification
- Drug Class: Non-steroidal Anti-Inflammatory Drug (NSAID)
- Therapeutic Use: Analgesic, Anti-inflammatory
- Prescription Status: Prescription-only medicine in many countries
How Does Aceclofenac Work?
Aceclofenac works by inhibiting the cyclo-oxygenase (COX) enzymes, mainly COX-2. These enzymes are responsible for the formation of prostaglandins, substances that trigger pain, inflammation, and swelling at injury sites.
By reducing prostaglandin synthesis, Aceclofenac helps:
- Decrease pain sensation
- Reduce inflammation and swelling
- Improve joint mobility
Uses of Aceclofenac
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute musculoskeletal pain
- Post-traumatic pain
- Dental pain (short-term)
Dosage and Administration
The dosage of Aceclofenac depends on the patient’s age, medical condition, and severity of pain.
- Common adult dose: 100 mg once or twice daily (as prescribed)
- Should be taken after meals to reduce gastric irritation
- Do not exceed the recommended dose
Note: Dosage must always be decided by a healthcare professional.
Possible Side Effects
Like all NSAIDs, Aceclofenac may cause side effects, though not everyone experiences them.
Common Side Effects
- Stomach pain or discomfort
- Nausea or vomiting
- Diarrhea
- Indigestion
Serious Side Effects (Rare)
- Gastrointestinal bleeding
- Kidney function impairment
- Allergic reactions
- Cardiovascular risk with long-term use
Seek immediate medical attention if severe symptoms occur.
Precautions and Warnings
- Use cautiously in patients with stomach ulcers
- Not recommended for severe kidney or liver disease
- Avoid alcohol during treatment
- Not advised during late pregnancy unless prescribed
Drug Interactions
Aceclofenac may interact with:
- Other NSAIDs
- Blood thinners (e.g., warfarin)
- Antihypertensive drugs
- Corticosteroids
Related Medical Topics
- Hypotension (Low Blood Pressure)
- Anasarca (Generalized Edema)
- Melena (Black Tarry Stool)
- Constipation
Trusted Medical References
- National Center for Biotechnology Information (NCBI)
- MedlinePlus
- NHS (UK)
- World Health Organization (WHO)
Frequently Asked Questions (FAQs)
Is Aceclofenac safe for long-term use?
Long-term use may increase the risk of gastrointestinal and cardiovascular side effects. It should only be used long-term under medical supervision.
Can Aceclofenac be taken daily?
Yes, but only if prescribed by a doctor and for a limited duration.
Is Aceclofenac stronger than paracetamol?
Yes. Aceclofenac has stronger anti-inflammatory action compared to paracetamol.
Can Aceclofenac cause stomach problems?
Yes. It may cause gastric irritation, ulcers, or bleeding in some individuals.
Is Aceclofenac an antibiotic?
No. Aceclofenac is a pain-relieving anti-inflammatory drug, not an antibiotic.
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