Albendazole is a broad-spectrum anthelmintic (anti-worm) medicine widely used to treat intestinal and tissue worm infections. It is listed in the WHO Essential Medicines List and commonly prescribed under the brand name Zentel.
What is Albendazole?
Albendazole is a benzimidazole derivative that works by stopping worms from absorbing glucose, leading to energy depletion and eventual death of the parasite. It is effective against roundworms, hookworms, pinworms, and tapeworms.
Diseases Treated with Albendazole (ICD-10 Based)
- Ascariasis (Ascaris lumbricoides) – ICD-10: B77
- Hookworm infection – ICD-10: B76
- Enterobiasis (Pinworm) – ICD-10: B80
- Hydatid disease – ICD-10: B67
- Neurocysticercosis – ICD-10: B69
Albendazole Dosage (Most Searched)
Adults
- Intestinal worms: 400 mg single dose
- Hydatid disease: 400 mg twice daily for 28 days (cycles)
Children
- Above 2 years: Same as adult dose
- 1–2 years: Dose adjusted by doctor
Zentel 400 mg is the most commonly prescribed tablet.
How Albendazole Works
Albendazole blocks microtubule formation in worms, inhibiting glucose uptake. This causes energy depletion, paralysis, and eventual death of the parasite, which is then expelled from the body.
Side Effects of Albendazole
Common Side Effects
- Nausea
- Abdominal pain
- Headache
- Dizziness
Rare but Serious Effects
- Elevated liver enzymes
- Hair loss (reversible)
- Bone marrow suppression (long-term use)
Drug Interactions
Albendazole may interact with other medicines. Use caution if you are taking:
- Metformin
- Ketoconazole
- Doxycycline
Albendazole vs Other Worm Medicines
- Albendazole vs Mebendazole: Albendazole is more effective for tissue worms.
- Albendazole vs Piperazine: Albendazole has broader coverage.
Precautions & Warnings
- Not recommended during pregnancy (especially first trimester)
- Liver function tests advised for long-term therapy
- Avoid alcohol during treatment
Frequently Asked Questions (FAQ)
Is Albendazole safe?
Yes, when taken as prescribed. Long-term use requires medical supervision.
Can children take Albendazole?
Yes, it is safe for children above 1 year under medical advice.
What is the price of Zentel?
Price may vary by location and pharmacy.
Can Albendazole cause constipation?
Rarely. Mild digestive discomfort is more common.
Is repeat dose necessary?
Yes, for pinworms a repeat dose after 2 weeks is often advised.
Can Albendazole be taken with food?
Yes, especially fatty meals improve absorption.
Medical Disclaimer
This content is for educational purposes only. Albendazole should not be taken without consulting a qualified healthcare professional. Dosage and duration depend on the type of infection and patient condition.
Source: WHO, BNF, CDC
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